In 'Kagaku Na Yatsura,' high school student Haruki Komaba is torn between two ridiculously well-endowed scientific geniuses: the half-cyborg robotics freak Airi Kuze and the busty canine-human hybrid Ayana Hizuki. Both girls are desperate to get Haruki into their respective clubs, resorting to insane and perverted scientific demonstrations that always spiral into hardcore sexual chaos. Ayana, a product of genetic splicing, frequently loses control, transforming into a monstrous bitch in heat, her massive tits spraying milk as she's ravaged by grotesque, tentacled creatures spawned from her own failed chemical experiments. Haruki is often caught in the middle, his cock relentlessly serviced by either Airi’s custom-built fuck-bots or a monstrously transformed Ayana who fucks him senseless with her mutated dog cunt. The chaos is amplified by Ayana's older sister, Touko, a slutty school nurse who uses her invisibility powers and chemical concoctions to instigate even more depraved threesomes and orgies, ensuring every experiment ends with bodies drenched in cum, milk, and various monstrous fluids.