In the perverted confines of the Kurokawa Clinic, the so-called 'Disgraceful Examination Room' lives up to its name under the depraved watch of its head doctor. The series follows the systematic sexual degradation of its female patients, beginning with the innocent Yuuko. Initially seeking treatment for a minor ailment, she is instead subjected to a series of humiliating and non-consensual 'examinations'. The doctor's fingers and medical instruments probe her most intimate orifices, forcing her into unwilling states of arousal. Her protests are ignored as he violates her mouth, pussy, and ass, documenting every lewd reaction. The arc expands to include other women like the timid Sanae and even the clinic's own nurse, Miki, who is blackmailed into participating. Each episode escalates the depravity, moving from forced groping and penetration to mind-breaking conditioning. The women are stripped, bound, and used as sexual playthings, their resistance eroding with each session until they are reduced to brainwashed, cum-craving slaves who obediently spread their legs for any depraved act the doctor desires, fully embracing their roles in his twisted medical theater.